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GDF-15 belongs to the transforming growth factor β superfamily. It is synthesized as a 62-kDa precursor protein, which, after cleavage by furin-like protease, is secreted as 25-kDa disulfidelinked dimmer. GDF15 is an important regulator of appetite and energy homeostasis. It exerts its effects via its receptor called glial-derived neurotrophic factor (GDNF) receptor alpha-like (GFRAL).
GDF-15 belongs to the transforming growth factor β superfamily. It is synthesized as a 62-kDa precursor protein, which, after cleavage by furin-like protease, is secreted as 25-kDa disulfidelinked dimmer. GDF15 is an important regulator of appetite and energy homeostasis. It exerts its effects via its receptor called glial-derived neurotrophic factor (GDNF) receptor alpha-like (GFRAL).
Catalogue Number: 42980
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