SAA is synthesized in the liver and secreted to the blood. When in the blood, SAA proteins form complexes with high density lipoproteins (HDL). It has been suggested that SAA is involved in the recycling of cholesterol from damaged tissues. Similar to C-reactive protein, SAA is a major acute phase protein in human being, it can be used in diagnosis, predicting outcomes and assessing the efficacy of treatment in patients with inflammation. SAA is a sensitive biomarker of acute renal allograft rejection and it can be used to monitor SAA in kidney transplant patients for the early detection of acute rejection episodes. In patients with myocardial infarction, SAA concentration is elevated to extremely high values and correlates with postinfarction complications and the mortality rate.
Catalogue Number: 41910
