• The dsDNA-specific autoantibodies (anti-dsDNA) are considered a specific marker for systemic lupus erythematosus (SLE), due to the high clinical associations1,2. The presence of anti-dsDNA autoantibodies in other pathological conditions and in healthy subjects is very rare (< 0.5%)3, in contrast, they may be present in SLE patients even before they develop clinical symptoms2, 3. Therefore, regular measurement of anti-dsDNA autoantibodies in blood is important for early diagnosis, as well as monitoring the progression of SLE.
• ELISA kit for quantitative measurement of anti-dsDNA autoantibodies in human blood samples, with superior reproducibility, specificity and sensitivity, ready for clinical application:

 Typical results
(Example only, not for calculation of actual results)

References:

1. D. A. Isenberg, et al. Fifty Years Of Anti-ds Dna Antibodies: Are We Approaching Journey’s End? Rheumatology, Vol. 46, No. 7, Pp. 1052–1056, 2007.
2. G. C. Tsokos. Systemic Lupus Erythematosus. The New England Journal Of Medicine, Vol. 365, No. 22, Pp. 2110–2121, 2011.
3. E. Cozzani, et al. Serology Of Lupus Erythematosus: Correlation Between Immunopathological Features And Clinical Aspects,” Autoimmune Diseases, Vol. 2014, Article Id 321359, 13 Pages, 2014.