Small nuclear ribonucleoprotein complexes (abbreviated as U-snRNP) are essential for splicing of precursor mRNA molecules and snRNPB is one of several nuclear proteins which are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs). Autoantibodies from patients with systemic lupus erythematosus (SLE) recognize epitopes on snRNPB/B’.
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