Micro-albumin(mALB), also known as urine albumin, is an important blood protein predominantly made by liver tissue that balances the blood osmotic pressure and transports hormones, vitamins, and substances like calcium throughout human body. Under normal circumstances, micro- albumin with 66kDa molecular weight is too large to cross the glomerular basal membrane. During kidney diseases, the pathological damage to the glomerular membrane leads to changes in permeability, and eventually causes micro-albumin excess excretion in urine. Therefore, micro-albumin is a sensitive and decisive biomarker for kidney injury. Micro-albumin test can timely detect kidney disease at early stage and help doctors make a right diagnosis to prevent deterioration. A higher level of micro-albumin in urine indicated the more severe kidney damage.
The reference of micro- albumin in health human is less than 20mg/L, and Reversible renal injury is among 20mg/L to 200mg/L, and Irreversible renal injury (renal failure or uremia) is above 200mg/L.
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