Annexin A8 (ANXA8) belongs to the annexin family of evolutionally conversed Ca2+ and phospholipid binding proteins. ANXA8 may function as an anticoagulant which inhibits the function of thromboplastin-specific complex in an indirect way. Overexpression of this gene has been shown to be associated with acute myelocytic leukemia.
Human ANXA8 shares 92.661% sequence identity with rat ANXA8 and 92.094% with mouse ANXA8.
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